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Prednisone may be prescribed along with other medications like analgesics and muscle relaxants depending on the severity of the disorder 1) In children 0-3 years of age, corticosteroids are generally prescribed to reduce spasms, seizures, and muscle spasms associated with ASD. 2) In adolescents 2-18 years of age, it is appropriate to use the corticosteroid in children with a developmental delay due to a developmental disorder, however, more extreme form of the disorder may require corticosteroids. A recent study showed the need to treat children with ASD with anti-inflammatory medications to prevent spasms. 3) In the adults of this age, corticosteroids are used as part of the treatment for ASD, however, an association between ASD and chronic medical conditions and the use of an anti-inflammatory compound could be an important consideration that should be explored. 1,2,3 Source(s): http://www.ncbi.nlm.nih.gov/pubmed/25809901 Vitamin D (D3) deficiency and ASD http://www.nature.com/articles/srep16086 Clinic Update: Vitamin D Supplements and Autism http://www.nursingworld.com/health/supplements/vitamin-d3-supplements-and-autism/ Vitamin D, the "gold standard" of nutritional intervention http://www.medscape.com/article/10.1236/bmj.h9078 Diseases Affected or Suppressed by D3 http://www.nursingworld.com/health/supplements/d3-diet-and-autoimmune-disorders/ Vitamin D, The "Perfect Diet for Autism" http://www.medscape.com/viewarticle/881838 Determination of vitamin D status using 25-hydroxyvitamin D http://www.ncbi.nlm.nih.gov/pubmed/10985089 Prevention of autoimmune diseases using vitamin D3 supplements http://www.healthaffairs.com/cgi/content/abstract/24/4/1057 How high are doses of vitamin D needed for a successful outcome in rheumatoid arthritis? http://www.mssoc.com/news/press-releases/2016/3rd-annual-review-on-rheumatoid-arthritis-drug- Related Article: